Philosophy
Robert L. McNeil Jr.
1915 to May 20th, 2010
"Robert L. McNeil Jr., chemist who promoted Tylenol, dies at 94"
After his family's drug company was sold to Johnson & Johnson, he became a philanthropist.
by
Thomas H. Maugh II
May 31, 2010
Los Angeles Times
Robert L. McNeil Jr., a Philadelphia chemist who developed a little-known pain reliever called paracetamol into the global blockbuster Tylenol, creating a fortune that he freely distributed to charities, universities and museums, died May 20 of a heart ailment at his home in Wyndmoor, Pa. He was 94.
McNeil was not a brilliant synthetic chemist discovering new compounds through long hours in the laboratory, said Arnold Thackray of the nonprofit Chemical Heritage Foundation, whose goal is to preserve the history of chemistry. Instead, he had the insight to discern that paracetamol, also known as acetaminophen, had the potential to become an important drug and the creativity to develop an effective marketing campaign.
Paracetamol was discovered by French chemist Charles Gerhardt in 1852, but the discovery languished for nearly a century until British researchers in the late 1940s demonstrated that it could safely and effectively alleviate pain and reduce fevers. About the same time, other research began to link excessive aspirin use to gastric bleeding and other problems.
Nonetheless, pharmaceutical companies were not interested in developing paracetamol because they feared that it would take sales away from their profitable aspirin products.
McNeil, research director for his family-owned McNeil Laboratories, saw a niche for the drug, guessing successfully that it could be marketed as a safe product for children. After commissioning safety and efficacy trials to obtain Food and Drug Administration approval, the company began marketing Tylenol Elixir for Children in 1955 as a prescription-only product. It was sold in a box shaped like a fire engine and carried the slogan "for little hotheads."
Eventually, the elixir and other Tylenol products for children and adults became available without prescriptions and the brand became one of the best-known drug names. Annual sales exceed $1 billion a year, despite the plethora of generic and branded products that compete with it.
Robert Lincoln McNeil Jr. was born in 1915 in Bethel, Conn., during a visit to his mother's parents. He graduated from Yale University in 1936, then earned a bachelor's degree from the Philadelphia College of Pharmacy and Science, now the University of the Sciences, in 1938.
After graduation, he joined the family business, which had been started by his grandfather as a neighborhood pharmacy in 1879. By the 1920s, the company had abandoned retail sales and was manufacturing drugs for sale to doctors and hospitals. It incorporated as McNeil Laboratories in 1933.
In 1955, Robert Sr. retired from the company and Robert Jr. became chairman of the board; his brother Henry became president. In 1959, the pair sold the company to Johnson & Johnson for about $33 million in stock. Robert Jr. remained as chairman of McNeil Laboratories until 1964 to ease the transition to corporate ownership.
After retirement, he became an active philanthropist, establishing the Barra Foundation — named after the McNeil clan's ancient home, the Isle of Barra off the west coast of Scotland — which gave generously to many Philadelphia-area institutions.
In 2005, he received the prestigious American Institute of Chemists Gold Medal for his pioneering work on acetaminophen — a name, incidentally, that he coined. A colleague suggested Tylenol, an abbreviation of the chemical name N-acetyl-p-aminophenol, for the brand name.
McNeil is survived by his wife, the former Nancy McKinney; two daughters, Victoria Le Vine and Joanna Lewis; two sons, Collin and Robert III; and 11 grandchildren.
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Philosophy
Deceased--Robert L. McNeil Jr.
Robert L. McNeil Jr.1915 to May 20th, 2010
"Robert L. McNeil Jr., chemist who promoted Tylenol, dies at 94"
After his family's drug company was sold to Johnson & Johnson, he became a philanthropist.
by
Thomas H. Maugh II
May 31, 2010
Los Angeles Times
Robert L. McNeil Jr., a Philadelphia chemist who developed a little-known pain reliever called paracetamol into the global blockbuster Tylenol, creating a fortune that he freely distributed to charities, universities and museums, died May 20 of a heart ailment at his home in Wyndmoor, Pa. He was 94.
McNeil was not a brilliant synthetic chemist discovering new compounds through long hours in the laboratory, said Arnold Thackray of the nonprofit Chemical Heritage Foundation, whose goal is to preserve the history of chemistry. Instead, he had the insight to discern that paracetamol, also known as acetaminophen, had the potential to become an important drug and the creativity to develop an effective marketing campaign.
Paracetamol was discovered by French chemist Charles Gerhardt in 1852, but the discovery languished for nearly a century until British researchers in the late 1940s demonstrated that it could safely and effectively alleviate pain and reduce fevers. About the same time, other research began to link excessive aspirin use to gastric bleeding and other problems.
Nonetheless, pharmaceutical companies were not interested in developing paracetamol because they feared that it would take sales away from their profitable aspirin products.
McNeil, research director for his family-owned McNeil Laboratories, saw a niche for the drug, guessing successfully that it could be marketed as a safe product for children. After commissioning safety and efficacy trials to obtain Food and Drug Administration approval, the company began marketing Tylenol Elixir for Children in 1955 as a prescription-only product. It was sold in a box shaped like a fire engine and carried the slogan "for little hotheads."
Eventually, the elixir and other Tylenol products for children and adults became available without prescriptions and the brand became one of the best-known drug names. Annual sales exceed $1 billion a year, despite the plethora of generic and branded products that compete with it.
Robert Lincoln McNeil Jr. was born in 1915 in Bethel, Conn., during a visit to his mother's parents. He graduated from Yale University in 1936, then earned a bachelor's degree from the Philadelphia College of Pharmacy and Science, now the University of the Sciences, in 1938.
After graduation, he joined the family business, which had been started by his grandfather as a neighborhood pharmacy in 1879. By the 1920s, the company had abandoned retail sales and was manufacturing drugs for sale to doctors and hospitals. It incorporated as McNeil Laboratories in 1933.
In 1955, Robert Sr. retired from the company and Robert Jr. became chairman of the board; his brother Henry became president. In 1959, the pair sold the company to Johnson & Johnson for about $33 million in stock. Robert Jr. remained as chairman of McNeil Laboratories until 1964 to ease the transition to corporate ownership.
After retirement, he became an active philanthropist, establishing the Barra Foundation — named after the McNeil clan's ancient home, the Isle of Barra off the west coast of Scotland — which gave generously to many Philadelphia-area institutions.
In 2005, he received the prestigious American Institute of Chemists Gold Medal for his pioneering work on acetaminophen — a name, incidentally, that he coined. A colleague suggested Tylenol, an abbreviation of the chemical name N-acetyl-p-aminophenol, for the brand name.
McNeil is survived by his wife, the former Nancy McKinney; two daughters, Victoria Le Vine and Joanna Lewis; two sons, Collin and Robert III; and 11 grandchildren.
- The Future Of Tv News
The last couple of weeks have seen a pair of contrasting retirement announcements in the TV news world. On the one hand, there was Katie Couric, a journalistic lightweight who tried to seem more serious with pre-prepared gotcha questions. On the other...
- Random Ironic Occurance Or Comic Design?
The intelligent design crowd thinks that the intricate nature of reality is evidence for the existence of their Creator, but complexity is one thing, an actual joke arising ex nihilo is another: So on the TSA's no-fly list is the name "Robert Johnson."...
- E-cigs Now Being Legally Challenged
"FDA can't regulate e-cigarettes as drug devices, appeals court rules" In a setback to the Food and Drug Administration, a three-judge federal panel says the agency should regulate electronic cigarettes as tobacco products and not drug-delivery...
- Something Cool During These "dog Days Of Summer"--a Hires Root Beer
Charles E. Hires August 19th, 1851 to August 1st, 1937 Wikipedia... Hires Root Beer was created by Philadelphia pharmacist Charles Elmer Hires. Hires first tasted root beer, (a traditional American beverage dating back to the colonial era), while on...
- Lexapro And Forest Laboratories...bad Ethics
Just more revelations of drug company greed and market manipulation. "A Drug Maker’s Strategy Revealed" by Gardiner Harris September 2nd, 2009 The New York Times The pharmaceutical industry has developed thousands of medicines that have saved millions...